LinkedIn: https://www.linkedin.com/in/dawid-rossino
Email:
Cycle: 40°
Curriculum: Ingegneria Chimica e dei Materiali
Title of the PhD Project: Process design, development and shelf-life of innovative micro-nanostructured polymeric products for biomedical applications
Supervisor(s): Caterina Cristallini; Maria Beatrice Coltelli
In Collaboration with : Consiglio Nazionale di Ricerca (CNR). Istituto dei processi chimico fisici (IPCF), sede secondaria di Pisa.
Abstract of the PhD project:
This Ph.D. project focuses on the development of micro and nanostructured polymeric products for biomedical applications. In particular, the research project starts with the production of polymeric scaffolds and micro-nanoparticles, moving towards more complex systems obtained by their integration. The research will also focus on the use of innovative production processes, in order to optimize the productivity and reproducibility of the polymeric devices. The purpose of the project is to obtain both biodegradable and biostable platforms able to provide a controlled and sustained drug release over time or a release in more steps. To achieve this, a wide study will be performed, from the definition of production protocols towards in vitro biological tests and in vivo implants, touching upon different knowledges, from chemistry to material science, biology and pharmaceutics. The expected outcome of the research project is the production of innovative bio-polymeric devices for biomedical applications capable to maximize the treatment efficacy, and to move towards a technological transfert.
Publications
Orcid ID: https://orcid.org/0009-0008-2846-5770
Articles:
2025 C.Cristallini, D.Rossin, R.Vanni, N.Barbani, C.Bulgheresi, M.Labardi, S.Perveen, S.Burchielli, D.Terlizzi, C.Kusmic, S.Del Ry, M.Cabiati C.Trouki, D.Rossino, F.Sergi, A.Villano, G.D.Aquaro, G.Scarpellino, F.A.Ruffinatti, S.Amorim, C.Giachino; A biodegradable, microstructured, electroconductive and nano-integrated drug eluting patch (MENDEP) for myocardial tissue engineering. Bioactive Materials, Elsevier, 2025, (IF 20.3). DOI: 10.1016/j.bioactmat.2025.04.008 Conferences
2025 C.Cristallini, D.Rossin, N.Barbani, R.Vanni, M.Labardi, C.Trouki, S.Burchielli, C.Kusmic, D.Terlizzi, F.Sergi, C.Bulgheresi, D.Rossino, E.Fiorino, M.Aubry, M.Lo Iacono, S.Perveen, G.Scarpellino, L.Munaron, S.Amorim, R.A. Pires, R.L. Reis, R.Rastaldo, C.Giachino Implementation of a Fully Biodegradable and Biomimetic Epicardial Patch Providing Synergic Physico-chemical, Mechanical and Electrical Cues for Myocardial Infarction Therapy. Biomaterial Advances, Elsevier, 2025, (IF 6). DOI: 10.1016/j.bioadv.2025.214523
Conferences:
2025 D.Rossino, C.Trouki, N.Barbani, F.Aiello, E.Tombari, M.Labardi, M.Aubry, R.Vanni, R.Rastaldo, C.Cristallini. Effect of an Engineered Interface on the Mechanical, Biodegradative and Functional Properties of a Multi- Layered Cardiac Patch. ESB2025-34th Annual Conference of the European Society for Biomaterials. 7-11 settembre 2025, Torino, Italia
2025 C.Trouki, D.Rossino, F.Aiello, M.Labardi, N.Barbani, C.Giachino, C.Cristallini. Molecular and physico-chemical characterization of multilayered PLGA/Gelatin based patches incorporating Fmoc-diphenilalanine for Myocardial Repair. ESB2025-34th Annual Conference of the European Society for Biomaterials. 7-11 September 2025, Turin, Italy,
2025 C.Trouki, D.Rossino, N.Barbani, F.Aiello, R.Vanni, R.Rastaldo, M.Pilato, G.Raffa, M.Rinaldi, E.Coscioni, G.Galasso, C.Giachino, C.Cristallini. Translating soft Science into Hard Impact: Toward a Scalable, Bioartificial Cardiac Patch.GreenChemCo 2025: Green Chemistry and Sustainable Coatings, 16-18 giugno 2025, Pisa, Italia,
2024 D.Rossino, C.Trouki, N.Barbani, M.Musetti, D.Rossin, R.Vanni, R.Rastaldo, C.Giachino, C.Cristallini. Evaluation of Ethylene Oxide Sterilization Effects on Multifunctional Micro-structured Patches for Chronic Myocardial Infarction SIB2024: Società Italiana dei Biomateriali, 8-10 June 2024, Faenza, Italy
2024 D.Rossino, G.Presciuttini, S.Linari, C.Cristallini, M.D’Acunto. New Wide-Range- Application Polymer Nanocomposites for Emerging Infectious Diseases SIB2024: Società Italiana dei Biomateriali, 8-10 giugno 2024, Faenza, Italia, Libro degli abstract p.169
2024 C.Trouki, D.Rossino N.Barbani, M.Labardi, E.Tombari, C.Cristallini. Development and Characterization of Multilayered Patches for Treating Acute and Chronic Myocardial Infarction SIB2024: Società Italiana dei Biomateriali, 8-10 giugno 2024, Faenza, Italia,
2024 D.Rossino, C.Trouki, N.Barbani, M.Musetti, D.Rossin, R.Vanni, R.Rastaldo, C.Giachino, C.Cristallini. Evaluation of Ethylene Oxide Sterilization Effects on Multifunctional Micro-structured Patches for Chronic Myocardial Infarction School of Nanomedicine 2024, 9-11 Ottobre 2024, Firenze, Italia